You can manage your global assemblies with the gacutil.exe which comes with Microsoft SDK. You can find this tool for instance in folder "C:\Program Files (x86)\Microsoft SDKs\Windows\v7.0A\Bin\".
This is an example about removing one assembly:
"C:\Program Files (x86)\Microsoft SDKs\Windows\v7.0A\Bin\gacutil.exe" /u Assembly.To.Uninstall